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Minicircle Follistatin Gene Therapy
The frontier of human longevity
The intersection of cutting-edge science, luxury and premier first-line longevity gene therapy.
Unlock your body’s true potential
“This gene therapy basically increases fat free mass, decreases body fat, rewinds cellular epigenetic age.”
“This gene therapy basically increases fat free mass, decreases body fat, rewinds cellular epigenetic age.”
Minicircle featured in the Netflix Bryan Johnson Documentary “Don’t Die: The Man Who Wants to Live Forever”
How it works
The science of extraordinary renewal
Minicircle’s proprietary therapy uses DNA plasmids to deliver temporary genetic instructions (Follistatin-344) that increase your body’s natural regenerative potential.
Why it's different
Unlike conventional treatments that temporarily mask symptoms, Follistatin gene therapy works at the cellular root—reprogramming your biology from the inside out.
Clinical outcomes at 90 days
muscle mass gained
biological age improvement
body fat percentage decrease
As seen on Netflix - "Don't Die" Documentary
The Teleios Experience
Science meets sanctuary
Private Concierge
State-of-the-Art Treatment Suites
Post-Treatment Recovery
Physician-Led Protocols
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Patient Testimonials & Transformation
Real people. Real results.
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The Process
Unlock your body’s deepest regenerative capabilities.
Where science meets elegance. Where healing becomes art.
Gene Therapies
Featured Treatment
Frequently Asked
Questions
A first-of-its-kind, single-dose non-integrating gene therapy that increases your body’s production of Follistatin-344, a protein that helps reduce aging signals, build lean muscle, decrease inflammation, and promote regenerative repair—all without altering your DNA or impacting fertility.
Follistatin works by neutralizing myostatin and activin—two proteins that restrict muscle growth and drive inflammation. By inhibiting these factors, Follistatin creates ideal conditions for the body to regenerate, build lean muscle, and heal more effectively.
No. Stem cell therapy introduces new cells into the body. Follistatin gene therapy, on the other hand, provides genetic instructions that empower your existing cells to repair and regenerate—treating the root cause rather than just the symptoms.
Results vary by individual, but clinical findings at 3 months post-treatment have shown:
↑ 2 lbs lean muscle mass
↓ 0.8% body fat
↓ Biological age by up to 12 years in some patients
Many also report better energy, performance, and an overall sense of vitality.
Results typically last around 12 months, though biological shifts—especially at the genetic and epigenetic level—may persist longer depending on lifestyle and overall health.
Yes. Follistatin-344 has been evaluated in both primate and human trials with an excellent safety profile, and no negative effects on fertility or immune function. This variant avoids the hormonal disruption sometimes seen with other forms like Follistatin-288.
About one-third of patients may experience a minor increase in LDL cholesterol (approximately 8 ng/dL). This is typically considered clinically insignificant, and is reviewed on a case-by-case basis during your medical consultation.
While innovative, Follistatin gene therapy is built on decades of scientific research. The role of Follistatin in muscle growth and inflammation was first identified in 2001, with subsequent animal and human studies reinforcing its potential. Our current protocol is the result of rigorous development and physician-led application.
Emerging research is promising. A 2021 study (Jajyan) showed a 32.5% increase in lifespan in mice treated with Follistatin. While human longevity data takes time, these results offer compelling early evidence.
Healthy adults looking to improve muscle tone, reduce fat, enhance energy, or proactively slow the aging process. It’s also well-suited for high-performance individuals, biohackers, and those with age-related muscle loss. A medical consultation is required to determine eligibility.
Follistatin gene therapy doesn’t mask symptoms—it reprograms your biology at the cellular level. Unlike creams, supplements, or hormone therapies, this treatment restores the body’s natural ability to regenerate, making it a functional, not just cosmetic, solution to aging.