Minicircle Follistatin Gene Therapy

The frontier of human longevity

As seen on

The intersection of cutting-edge science, luxury and premier first-line longevity gene therapy.

Build lean muscle mass
Lose body fat
Gain back years of biological age

Take control of your well-being

Unlock your body’s true potential

Restore strength and vitality

Redefine aging

Recognized by

How it works

The science of extraordinary renewal

Minicircle’s proprietary therapy introduces genetic instructions
(Follistatin-344) that help your body increase its regenerative potential.

Follistatin-344 inhibits two key molecules:
Myostatin
Limits muscle growth
Activin
Contributes to inflammation
Delivered through a single subcutaneous fat injection with results that typically last up to one year

Why it's different

Unlike conventional treatments that temporarily mask symptoms, Follistatin gene therapy works at the cellular root—reprogramming your biology from the inside out.

Targets frailty, inflammation, and biological aging
Reverses epigenetic age by up to 12 years in clinical trials
Backed by decades of primate and human safety data
Improves strength and body composition naturally

Clinical outcomes at 90 days

+2 lbs

muscle mass gained

-12 years

biological age improvement

-0.8%

body fat percentage decrease

The Teleios Experience

Clinical outcomes at 90 days

+2 lbs
lean muscle mass
-0.8%
body fat percentage
-12 years
biological age

Follistatin Gene Therapy

A new era in healing

This is not cosmetic enhancement. This is regenerative restoration, guided by cellular science and delivered with elegance.

before
After

As seen on Netflix - "Don't Die" Documentary

The Teleios Experience

Science meets sanctuary

Through our exclusive partner clinic Proactive Longevity in Cabo, you’ll receive groundbreaking treatments in a luxury setting designed for healing, privacy, and personalized care.

Private Concierge

Personalized planning and support

State-of-the-Art Treatment Suites

Designed for both comfort and performance

Post-Treatment Recovery

Restorative care with refreshments and attentive service

Physician-Led Protocols

Administered by leading specialists in regenerative medicine
Teleios officeTeleios officeTeleios officeTeleios office

Patient Testimonials & Transformation

Real people. Real results.

“We serve life and give it the home that honors it most deeply.”
Mac Davis
Founder & CEO -
Whether you're reversing the effects of time or preparing to thrive through it, Minicircle Follistatin therapy offers a future where you don’t just live longer—you live stronger.

The Process

Unlock your body’s deepest regenerative capabilities.

Complimentary Consultation
Begin with a personal session with one of our concierge patient care coordinators, ensuring a seamless journey.
Tailored Medical Assessment
Complete our medical questionnaire at your convenience to determine your suitability for treatment, or opt for a guided walkthrough over a phone call.
Medical Intake & Eligibility Screening
Engage in a detailed consultation with one of our world-class medical doctors, who will comprehensively evaluate your health needs.
Bespoke Luxury Care
Once your treatment is confirmed, our concierge team will connect you with our partner clinic, Proactive Longevity in Cabo, and coordinate private car service to and from the clinic. If desired, we can also arrange airport pickup and drop-off or transfers to and from your hotel. We’re pleased to offer personalized hotel recommendations and curated local guidance, ensuring your visit is as seamless and inspiring as your treatment.
Ongoing Post-Treatment Care
Our commitment to you extends beyond the procedure. We offer continued support and assistance after you return home, recognizing and valuing your unique needs and long-lasting well-being.

Where science meets elegance. Where healing becomes art.

Gene Therapies

Featured Treatment

Follistatin Gene Therapy
A groundbreaking treatment for lean muscle, biological age reversal, and longevity.
*Minicircle is a gene therapy platform, not a medical provider. All therapies are investigational, have not been reviewed by the FDA, and are administered by licensed clinicians at independent international partner clinics operating under regulatory frameworks outside the United States.
1mL
Monad Essential
Targeted IV or skin therapy for a cellular boost.
Explore Exosome Therapy
2mL
Monad Advanced
Pair skin and IV therapies for amplified effect.
Explore Exosome Therapy
-
Monad Premium
A multi-treatment experience in a single day or over two.
Explore Exosome Therapy
3mL
Hair Restoration
Our full follicle-reactivation therapy.
Explore Exosome Therapy
Follistatin Gene Therapy
A groundbreaking treatment for lean muscle, biological age reversal, and longevity.
Explore Gene Therapy

Frequently Asked
Questions

A first-of-its-kind, single-dose non-integrating gene therapy that increases your body’s production of Follistatin-344, a protein that helps reduce aging signals, build lean muscle, decrease inflammation, and promote regenerative repair—all without altering your DNA or impacting fertility.

Follistatin works by neutralizing myostatin and activin—two proteins that restrict muscle growth and drive inflammation. By inhibiting these factors, Follistatin creates ideal conditions for the body to regenerate, build lean muscle, and heal more effectively.

No. Stem cell therapy introduces new cells into the body. Follistatin gene therapy, on the other hand, provides genetic instructions that empower your existing cells to repair and regenerate—treating the root cause rather than just the symptoms.

Results vary by individual, but clinical findings at 3 months post-treatment have shown:

↑ 2 lbs lean muscle mass
↓ 0.8% body fat
↓ Biological age by up to 12 years in some patients

 Many also report better energy, performance, and an overall sense of vitality.

Results typically last around 12 months, though biological shifts—especially at the genetic and epigenetic level—may persist longer depending on lifestyle and overall health.

Yes. Follistatin-344 has been evaluated in both primate and human trials with an excellent safety profile, and no negative effects on fertility or immune function. This variant avoids the hormonal disruption sometimes seen with other forms like Follistatin-288.

About one-third of patients may experience a minor increase in LDL cholesterol (approximately 8 ng/dL). This is typically considered clinically insignificant, and is reviewed on a case-by-case basis during your medical consultation.

While innovative, Follistatin gene therapy is built on decades of scientific research. The role of Follistatin in muscle growth and inflammation was first identified in 2001, with subsequent animal and human studies reinforcing its potential. Our current protocol is the result of rigorous development and physician-led application.

Emerging research is promising. A 2021 study (Jajyan) showed a 32.5% increase in lifespan in mice treated with Follistatin. While human longevity data takes time, these results offer compelling early evidence.

Healthy adults looking to improve muscle tone, reduce fat, enhance energy, or proactively slow the aging process. It’s also well-suited for high-performance individuals, biohackers, and those with age-related muscle loss. A medical consultation is required to determine eligibility.

Follistatin gene therapy doesn’t mask symptoms—it reprograms your biology at the cellular level. Unlike creams, supplements, or hormone therapies, this treatment restores the body’s natural ability to regenerate, making it a functional, not just cosmetic, solution to aging.